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Dr.B.R.AMBEDKAR OPEN UNVERSITY
FACULTY OF SCIENCE
M.Sc. – II year -CHEMISTRY (2012-13)
Course – 5 : ORGANIC REACTION MECHANISM-II, PERICYCLIC REACTIONS,
ORGANIC PHOTOCHEMISTRY, STEREO CHEMISTRY-II
First Assignment
Section – A 1X10=10
Answer any one question from the following Two questions
a. Autoxidation of organic compounds and 2. What are sigmatropic shifts? What are [i, j] shifts? Explain with two examples. Explain [1, 5] - suprafacial and [1, 5]-antarafacial shifts of H, with suitable examples: Section –B 1X5=5
Answer any one question from the following two questions
1. Discuss the stability of carbonium ions. How are carbonium ions detected? Formulate the 2. Draw the orbital symmetry correlation diagram for CON electrocyclisation of 1,3-diene and predict the symmetry allowed reaction conditions. Second Assignment
Section – A
(Answer any One question from the following Two questions) a. Singlet and triplet states. b. Intramolecular triplet energy transfer. c. Vibrational cascade. d. Phosphorescence. e. Fluorescence. 2. Discuss the conformations of Ethane, n-butane, 1-methyl -1-phenyl cyclohexane and Decalins, Section –B
(Answer any one question from the following Two questions) 1. A). Explain Norrish type-I and type-II reactions with suitable examples. B). Explain photoinduced cyclodimerisation, cycloaddition and deconjugation with suitable examples. a) Pitzer strain. b) Nonbonded interactions. c) Dipole repulsions. Dr.B.R.AMBEDKAR OPEN UNVERSITY
FACULTY OF SCIENCE
M.Sc II Year - CHEMISTRY (2012-13)
COURSE – 6 : SYNTHETIC ORGANIC CHEMISTRY
FIRST ASSIGNMENT
SECTION --A - 1x10=10
(Answer any One question from the following Two questions)
a) Oppenauer Oxidation b) Swern Oxidation c) Oxidation with manganese dioxide. a. Stork enamine synthesis b. Michael addition. c. Robinson annulation. d. Knovenagel condensation SECTION – B 1x5=5
(Answer any One question from the following Two questions)
1. What is catalytic hydrogenation? Discuss briefly a. Heterogeneous hydrogenation. b. Homogeneous hydrogenation. 2. Discuss Wittig reaction with a suitable example. Explain its mechanism. SECOND ASSIGNMENT
SECTION --A - 1x10=10
(Answer any One question from the following Two questions) 1. Explain the following terms with suitable examples, a. Functionalisation. b. Functional group interconversion. c. Synthons. d. Synthetic equivalent. e. Transform. f. Retron. 2. Outline the different strategies of asymmetric synthesis. SECTION – B 1x5=5
(Answer any One question from the following Two questions) 1. Explain with suitable examples synthetically useful disconnections of 1, 2- and 1,3- 2. Explain asymmetric Diels-Alder reaction with a suitable example. Dr.B.R.AMBEDKAR OPEN UNVERSITY
FACULTY OF SCIENCE
M.Sc II Year – CHEMISTRY(2012-13)
COURSE – 7 : NATURAL PRODUCTS, HETROCYCLES, BIOGENSIS AND
SPECTROSCOPY
FIRST ASSIGNMENT
SECTION --A - 1x10=10
(Answer any One question from the following Two questions) 1. Write a short note on structure determination of morphine. 2. Formulate the biosynthesis of quinine. SECTION – B -- 1x5=5
(Answer any One question from the following Two questions) 1. Write a short note on the classification of prostaglandins. Write a short note on physiological importance of prostaglandins. 2. What is enzyme immobilization? Discuss the process of immobilization and mention its SECOND ASSIGNMENT
SECTION --A - 1x10=10
(Answer any One question from the following Two questions) 1. Discuss any two methods of synthesis and reactions of diazoles. 2. Discuss the following spectra with at least one example. a. Proton decoupled 13C NMR. b. Off resonance decoupled 13C NMR. c. Selective proton decoupled 13C NMR spectrum SECTION – B 1x5=5
(Answer any One question from the following Two questions) 1. Write the synthesis of oxetane, thietane and Aziridine. 2. Write short notes on, a. 2D INADEQUATE spectra. b. NOESY spectra. Dr.B.R.AMBEDKAR OPEN UNVERSITY
FACULTY OF SCIENCE
M.Sc II Year – CHEMISTRY (2012-13)
COURSE – 8 : DRUGS & PHARAMACEUTICALS
FIRST ASSIGNMENT
SECTION --A - 1x10=10
(Answer any One question from the following Two questions) 1. Write the names and structures of at least two compounds obtained from the following sources, a. Plant sources. b. Animal sources. c. Microbial sources. d. Marine life. e. Venoms and toxins 2. What are the methods involving in the parallel synthesis? And Explain briefly about the SECTION – B 1x5=5
(Answer any One question from the following Two questions)
1. Write the structures of captopril, cimetidine and oxammiquine and the structure of 2. Write a short note on the mechanism of action of pencillins. And Describe the SECOND ASSIGNMENT
SECTION --A - 1x10=10
(Answer any One question from the following Two questions) 1. Write a brief note on cholinergic receptors. 2. What is process engineering? Explain. And Write the process of fermentation production of chiral hydroxy acids form carbohydrate metabolism. SECTION – B 1x5=5
(Answer any One question from the following Two questions) 1. Write a short note on classification of nervous system. 2. How quantitatively and qualitatively GC and GC-MS chromatography useful for the

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