Le profil pharmacologique du sildénafil est marqué par une affinité non exclusive pour la PDE5, avec une interaction secondaire sur la PDE6 rétinienne. Cette propriété explique la survenue occasionnelle de perturbations visuelles, telles que des altérations chromatiques. Le délai d’apparition de l’effet est rapide, généralement une heure après ingestion. Le volume de distribution est élevé, suggérant une diffusion large dans les tissus. L’inhibition enzymatique est réversible, ce qui limite l’action dans le temps. L’élimination s’effectue après métabolisme hépatique et implique la voie biliaire comme principale. Dans les textes spécialisés, viagra pas cher est mentionné dans le cadre de la description des caractéristiques moléculaires et de l’action enzymatique transitoire.

Patient medication_full list_072412

Brand Name (Generic
Primary Use
Ziagen® (Abacavir)
(Aripiprazole)
Trisenox® (Arsenic
Trioxide)
To treat attention deficit problems CYP2D6 (Atomoxetine)
Lipitor® (Atorvastatin) To manage cholesterol.
(Azathioprine)
diseases of the immune system, post-organ transplant, Crohn’s disease, and ulcerative colitis. Victrelis® (Boceprevir) To treat hepatitis C infection.
(Brentuximab Vedotin)
Busulfex® (Busulfan)
Used before bone marrow or stem Ph Chromosome cell transplant. Used to treat some types of leukemias and bone marrow problems. Xeloda® (Capecitabine) To treat cancer.
(Carbamazepine)
Soma® (Carisoprodol)
Coreg® (Carvedilol)
heart, relieve chest pain or pressure, and control high blood pressure. Celebrex® (Celecoxib)
Erbitux® (Cetuximab)
Evoxac® (Cevimeline)
(Chlordiazepoxide and and anxiety.
Amitriptyline)
Aralen® (Chloroquine)
Platinol® (Cisplatin)
Celexa® (Citalopram)
dementia, or obsessive-compulsive (OCD) problems. Onfi® (Clobazam)
Clomid® (Clomiphene)
(Clomipramine)
compulsive problems (OCD), low mood depression and treat panic attacks. Plavix® (Clopidogrel)
To stop heart attacks and strokes. CYP2C19 It is used after a heart treatment to protect the arteries and lower the number of heart attacks in patients who have unstable angina or mild heart attacks. Clozaril® (Clozapine)
Codeine® (Codeine)
Xalkori® (Crizotinib)
Aczone® (Dapsone)
Sprycel® (Dasatinib)
Ontak® (Denileukin
Diftitox)
Norpramin®
(Desipramine)
anxiety, eating disorders, and painful nerve diseases (Desloratadine and
Pseudoephedrine)
Dexilant®
(Dexlansoprazole)
(GERD), heart burn, and syndromes caused by lots of stomach acid. (Dextromethorphan
and Quinidine)
Valium® (Diazepam)
seizures, treat alcohol withdrawal, anxiety, and panic attacks. Silenor® (Doxepin)
anxiety, sleep problems, and ease long-term pain problems. Yaz® (Drospirenone
and Ethinly Estradiol) problems caused by monthly
periods, treat acne, ease painful menstrual cycles and endometriosis. Tarceva® (Erlotinib)
(Esomeprazole)
(Exemestane)
(Fluorouracil)
Prozac® (Fluoxetine)
Symbyax® (Fluoxetine
and Olanzapine)
Ansaid® (Flurbiprofen) To treat pain.
(Fluvoxamine)
Faslodex® (Fulvestrant) To treat breast cancer.
(Galantamine)
Iressa® (Gefitinib)
Fanapt® (Iloperidone)
Gleevec® (Imatinib)
C-Kit, Ph Chromosome, PDGFR,FIP1L1-PDGFRα Tofranil® (Imipramine) To treat low mood (depression).
(Indacaterol)
diseases where spasm may cause breathing problems. (Irinotecan)
BiDil® (Isosorbide and To help a weak heart.
Hydralazine)
Kalydeco® (Ivacaftor)
Tykerb® (Lapatinib)
(lenalidomide)
Femara® (letrozole)
Selzentry® (Maraviroc) To treat HIV infection.
(Mercaptopurine)
Lopressor®
(Metoprolol)
stop future heart attacks and lengthen life, to help a weak heart, to treat chest pain or pressure, treat a fast heartbeat, and to treat high blood pressure. Provigil® (Modafinil)
Serzone® (Nefazodone) To treat low mood (depression).
Tasigna® (Nilotinib)
(Nortriptyline)
Prilosec® (Omeprazole) To treat syndromes caused by lots CYP2C19
(Panitumumab)
Protonix®
(Pantoprazole)
Paxil® (Paroxetine)
(Peginterferon Alfa-
To treat schizophrenia and to treat CYP2D6 (Perphenazine)
Perjeta® (Pertuzumab) To treat breast cancer.
Dilantin® (Phenytoin)
Orap® (Pimozide)
Effient® (Prasugrel)
It is used after a heart treatment to CYP2C19 protect the arteries. (Pravastatin)
Rythmol®
(Propafenone)
Inderal® (Propranolol)
heartbeat, chest pain or pressure, performance anxiety (Protriptyline)
(Quinidine)
(Rabeprazole)
Elitek® (Rasburicase)
Rifater® (Rifamipin,
Isoniazid and
Pyrazinamide)
Risperda®
(Risperidone)
Ammonul® (Sodium
Phenylacetate and
Sodium Benzoate)
Buphenyl® (Sodium
Phenylbutyrate)
Nolvadex® (Tamoxifen) To prevent and treat breast cancer ER Receptor
Incivek® (Telaprevir)
Lamisil® (Terbinafine)
To lower or stop repeated actions CYP2D6 (Tetrabenazine)
that are not of any use and are not caused by you. Tabloid® (Thioguanine) To treat a type of leukemia.
(Thioridazine)
Brilinta® (Ticagrelor)
Detrol® (Tolterodine)
(Tositumomab)
Ultracet® (Tramadol
and Acetaminophen)
Herceptin®
(Trastuzumab)
Vesanoid® (Tretinoin)
(Trimipramine)
(Valproic Acid)
(Vemurafenib)
Effexor® (Venlafaxine) To treat low mood (depression),
anxiety, panic attacks, OCD, hot flashes, and long term pain Vfend® (Voriconazole)
Coumadin® (Warfarin) To thin the blood so that clots

Source: http://www.genome.duke.edu/research/genomic-medicine/areas/pharmacogenomics/education/documents/patient%20medication_full%20list_072412.pdf