Annex iv

PROHIBITED SUBSTANCES

Horses taking part in a competition must be healthy and compete on their inherent merits. The use of a Prohibited Substance might influence a horse's performance or mask an underlying health problem and could falsely affect the outcome of a competition. The list of Prohibited Substances has been compiled to include all categories of pharmacological action. The following are prohibited substances: Substances capable at any time of acting on one or more of the following mammalian body systems: the digestive system other than certain specified substances for the oral treatment of gastric ulceration. See Note 1 the skin (e.g. hypersensitising agents). the immune system, other than those in licensed vaccines against infectious Antipyretics, analgesics and anti-inflammatory substances. Cytotoxic substances. Endocrine secretions and their synthetic counterparts Masking agents. A finding of a prohibited substance means a finding of the substance itself or a metabolite of the substance or an isomer of the substance or an isomer of a metabolite. The finding of any scientific indicator of administration or other exposure to a prohibited substance is also equivalent to the finding of the substance. With the objective of helping riders, trainers and their veterinary advisers, the FEI may include in its rules examples of prohibited substances. Note 1: Oral treatment by the histamine H2-receptor antagonists ranitidine,
cimetidine and the proton pump inhibitor omeprazole is permitted and will not
necessitate the use of a medication form.
Note 2: Treatment of mares for oestrus-related behavioural problems is
permitted with the substance altrenogest (e.g. Regumate) under the following
conditions:
1. It is only permitted for mares with an oestrus-related behavioural
problem.
2. The dose and duration of treatment must be in accordance with the
manufacturers’ recommendations.
3. A Medication Form 2 must be completed by a veterinarian and
submitted to the Veterinary Delegate/Commission before the start of
the event.
Notes 1 and 2 will be reviewed annually by the FEI.
Thresholds

Thresholds can only be adopted for:
Substances endogenous to the horse Substances arising from plants traditionally grazed or harvested as equine feed Substances in equine feed arising from contamination during cultivation, processing or treatment, storage or transportation. Thresholds shall be recommended by the Medication Sub Committee, after consultation with official analysts and veterinarians, and approved annually by the General Assembly. Substances below the following thresholds are not actionable:
Available Carbon dioxide

Boldenone
free and conjugated boldenone 0.015 6g per
Dimethyl sulphoxide
15 micrograms per mil ilitre in urine or Estranediol in male Horses
the mass of free and conjugated 5a-estrane-3b, 17a-diol to the mass of free and conjugated 5(10)-estrene-3b, 17a-diol in urine from male
Hydrocortisone

Salicylic acid 625

Testosterone
0.02 micrograms free and conjugated Testosterone per 0.055 microgram free and conjugated testosterone per mil ilitre in urine from fil ies and mares (unless in foal).
Theobromine
For any finding of a prohibited substance of endogenous nature, the FEI may decide either itself or at the rider’s or trainer’s request to examine the horse further.

Source: http://www.staldelindeboom.nl/ver/downloads/verbodenmiddelen.pdf