Exploitation of a Candida antarctica lipase B-catalyzed in situ carboxylic acid activation method for the synthesis of acetanilides: Samridhi Lal and Timothy J. Snape,* Journal of Molecular Catalysis B: Enzymatic, 2012, In Press.
Thermodynamic interactions of a cis and trans benzanilide with Escherichia coli bacterial membranes: Sarah R. Dennison, David A. Phoenix and Timothy J. Snape, European Biophysics Journal, 2012,doi:10.1007/s00249- 012-0835-3.
Exploiting conformationally restricted N,N’-dimethyl-N,N’-diarylureas as biologically active C=C double bond analogues: synthesis and biological evaluation of combretastatin A-4 analogues: Timothy J. Snape,* Katherine Karakoula, Farzana Rowther and Tracy Warr, RSC Adv., 2012, 2 (19), 7557 - 7560.
Synthesis of 1,3-disubstituted azetidines via a tandem ring-opening ring-closing procedure: Andrea March- Cortijos, Timothy Snape* and Nicholas Turner, Synlett, 2012, 23, 1511-1515.
Interactions between suitably functionalised conformationally distinct benzanilides and phospholipid monolayers: Sarah R. Dennison, Zaheer Akbar, David A. Phoenix and Timothy J. Snape,*Soft Matter, 2012, 8 (11), 3258 - 3264.
Exploiting conformationally restricted ureas as biologically active C=C double bond analogues against GBM cells in vitro, TJ Snape, A Karakoula, F Rowther and TJ Warr, Neuro. Oncol., 2011, 13 (suppl 2): ii1-ii14.
Towards establishing the effects and mechanism of action of a series of indoles in an in vitro chemosensitivity system for glioma treatment, Saurabh Prabhu, Frederick Harris, Robert Lea and Timothy J Snape, Neuro. Oncol., 2011, 13 (suppl 2): ii1-ii14.
Effects of Momordica charantia fruit extract with the combination of temozolamide and cisplatin in the treatment of glioma cancer: G. Manoharan, R. W. Lea, T. J. Snape, J. Singh*, Proc. Physiol. Soc., 2010, 18, PC22.
Roberts, Stanley Michael; Santoro, Maria Gabriella; Jadhav, Vasudev; Happe, Alan Michael; Evans, Paul; Ross, Nicolette Christa; Snape, Timothy James, Patent Number: US 07759399, Publication Date: July 20, 2010, Crawford Healthcare Holdings Limited .
Understanding the chemical basis of drug stability and degradation: Timothy J. Snape*, Alison M. Astles and Janice Davies, The Pharmaceutical Journal,2010, 285, 416.
The process of drug development from the laboratory bench to the market: Timothy J. Snape* and Alison M. Astles, The Pharmaceutical Journal,2010, 285, 272.
The rational redesign of penicillins to help combat penicillin resistance: Timothy J. Snape* and Alison M. Astles, The Pharmaceutical Journal,2010, 285,162.
Take a close look at citalopram and you can predict its contraindications: Timothy J. Snape* and Alison M. Astles, The Pharmaceutical Journal,2010, 285, 59 - Cover Article.
Monoamine Oxidase (MAO-N) Catalysed Reactions: Application Towards the Chemo-Enzymatic Deracemisation of the Alkaloid (±)-Crispine A: Andrew J. Ellis, Renate Reiss, Timothy J. Snape and Nicholas J. Turner, Practical Methods for Biocatalysis and Biotransformations, 2009, John Whittall, Peter Sutton (Eds), Wiley, Chapter 11.1.
Towards a chemo-enzymatic method for the asymmetric synthesis of β-amino tertiary alcohols: Andrea March- Cortijos and Timothy J. Snape*, Org. Biomol. Chem., 2009, 7, 5163-5165.
Versatility of a new bioinorganic catalyst: Palladized cells of Desulfovibrio desulfuricans and application to dehalogenation of flame retardant materials, K. Deplanche; T. J. Snape; S. Hazrati; S. Harrad; L. E. Macaskie*, Environmental Technology, 2009, 30, 7, 681–692.
Helix Persistence and Breakdown in Oligoureas of Metaphenylenediamine: Apparent Diastereotopicity as a Spectroscopic Marker of Helix Length in Solution: Jonathan Clayden*, Loic Lemiegre, Gareth A. Morris, Mark Pickworth, Timothy J. Snape and Lyn H. Jones, J. Am. Chem. Soc., 2008, 130, 15193–15202.
α-Arylation of Aryl-Ketones: Expanding the Scope of the Truce-Smiles Rearrangement: Timothy J. Snape*, Synlett, 2008, 2689-2691.
A Truce on the Smiles Rearrangement: Revisiting an Old Reaction – The Truce-Smiles Rearrangement: Timothy J. Snape*, Chem. Soc. Rev., 2008, 11, 2452-2458.
A biogenic catalyst for hydrogenation, reduction and selective dehalogenation in non-aqueous solvents: N. J. Creamer, K. Deplanche, T. J. Snape, I. P. Mikheenko, P. Yong, D. Samyahumbi, J. Wood, K. Pollmann, S. Selenska-Pobell and L. E. Macaskie*, Hydrometallurgy, 2008, 94, 138-143.
Enzymatic desymmetrisation of (2-hydroxymethyl-oxiranyl)-methanol in organic solvents: Andrea March Cortijos and Timothy J. Snape*, Tetrahedron: Asymmetry, 2008, 19, 15, 1761-1763.
Recent Advances in the Semi-Pinacol Rearrangement of α-Hydroxy Epoxides and Related Compounds: Timothy J. Snape*, Chem. Soc. Rev., 2007, 36, 11, 1823-1842.
A Template-Based Mnemonic for Monoamine Oxidase (MAO-N) Catalyzed Reactions and its Application Towards the Chemo-Enzymatic Deracemisation of the Alkaloid (±)-Crispine A: Kevin R. Bailey, Andrew J. Ellis, Renate Reiss, Timothy J. Snape* and Nicholas J. Turner*, Chem. Commun., 2007, 3640-3642. Designated a Chem. Commun. “Hot Article”
Achieving conformational control over C-C, C-N and C-O bonds in biaryls, N,N’-diarylureas and diaryl ethers: advantages of a relay axis: Mark S. Betson, Ann Bracegirdle, Jonathan Clayden*, Madeleine Helliwell, Andrew Lund, Mark Pickworth, Timothy J. Snape and Christopher P. Worrall, Chem. Commun., 2007, 7, 754- 756.
Application of the Semi-Pinacol Rearrangement Towards the Generation of Alkenyl-Substituted Quaternary Carbon Centres: Timothy J. Snape*, Org. Biomol. Chem., 2006, 4, 4144-4148.
Induction of Apoptosis in Estrogen-Receptor Negative Breast Cancer Cells by Natural and Synthetic Cyclopentenones: Role of the IKK/NF-κB Pathway: Ciucci A, Gianferretti P, Piva R, Guyot T, Snape TJ, Roberts SM and Santoro MG*, Mol. Pharmacol., 2006, 70, 1812-1821.
Synthesis of 4-azacyclopent-2-enones and 5,5-dialkyl-4-azacyclopent-2-enones: Dauvergne J, Happe AM*, Jadhav V, Justice D, Matos MC, McCormack PJ, Pitts MR, Roberts SM, Singh SK, Snape TJ, Whittall J, Tetrahedron, 2004, 60, 2559-2567.
Synthesis and revision of the stereochemistry of a cyclopentenone natural product isolated from ascomycete strain A23-98:Bickley JF, Roberts SM, Santoro AG, Snape TJ*, Tetrahedron, 2004, 60, 2569-2576.
The IκB kinase IKK is the molecular target for anti-herpetic cyclopentenones: Amici C, Belardo G, Ciucci A, Volpi C, Guyot T, Evans P, Happe A, Snape T, Roberts S, Santoro MG*, Antiviral Research, 2003, 57, 3, A58-A58.
Roberts Stanley Michael; Ross Nicolette Christa; Jadhav Vasudev; Evans Paul; Snape Timothy James; Happe Alan Michael; Santoro Gabriella Maria, Patent Number: AU2003224244, Publication Date: 2003-10-13, Charterhouse Therapeutics Ltd.
Speech for President Joy Baluch South Australian Infrastructure Conference The Investment Future for the Next Boom State 1.40pm - 28 August 2008 Rendezvous Allegra Hotel Adelaide “Urban Planning and Social Infrastructure Requirements Moving Forward” Good afternoon and thank you for the opportunity to speak to you today at the South Australian Infrastructure Confe
Three-Tier Plan 2011 CIGNA Choosing the medication that is right for you offer an extensive list of brand and generic Choosing where to fill your medication should be easy, too. With over 60,000 pharmacies network, you will have convenient access to your medications – whether you pick them up, or Enclosed you will find a list of medications covered by your plan, in an easy-to-read