It is as if my life were magically run by two electric currents: joyous positive and despairing negative - whichever is running at the moment dominates my life, floods it.
Delia Villasenor, Stephen Brock, & Beth Hopper
Sylvia Plath (2000)The Unabridged Journals of Sylvia Plath, 1950-1962New York: Anchor Books
Best Practices for School Psychologists
Best Practices for School Psychologists
One or more Manic Episode or Mixed Manic
Numerous periods with hypomanic and depressive
Minor or Major Depressive Episodes often present
No full Manic, Major Depressive, or Mixed
Bipolar features that do not meet criteria for any specific bipolar disorder.
A distinct period of abnormally and persistently elevated, expansive, or irritable mood.
Causes marked impairment in occupational functioning in usual social activities or
relationships, or
Three or more (four if the mood is only irritable) of the following symptoms:
Necessitates hospitalization to prevent harm to self or others, or
Pressured speech or more talkative than usual
Not due to substance use or abuse (e.g., drug
abuse, medication, other treatment), or a
Psychomotor agitation or increase in goal-directed
Euphoria: Elevated (too happy, silly, Decreased Need for Sleep:
inappropriate reaction to external events
Irritability: Energized, angry, raging, or
intensely irritable mood, “out of the blue”
Increased Speech: Dramatically A child suddenly begins to talk
or as an inappropriate reaction to external flies into a violent 20-
amplified volume, uninterruptible extremely loudly, more rapidly, and
events for an extended period of time. Inflated Self-Esteem or Grandiosity: Flight of Ideas or Racing
Believing, talking or acting as if he is
Thoughts: Report or observation rambling speech that is out of
special powers or abilities despite clear
From Lofthouse & Fristad (2006, p. 215)
From Lofthouse & Fristad (2006, p. 215)
Distractibility: Increased Increase in Goal-Directed Activity or Psychomotor Agitation: Hyper-
focused on making friends, engaging everyone’s desks, or plan to in multiple school projects or hobbies build an elaborate fort in the
Excessive Involvement in
May not be viewed by the individual as pathological
Pleasurable or Dangerous
However, others may be troubled by erratic behavior
Activities: Sudden unrestrained
participation in an action that is likely jump out of a moving school to lead to painful or very negative
From Lofthouse & Fristad (2006, p. 215)
Major Depressive Episode Criteria (cont.)
A period of depressed mood or loss of interest or
Causes marked impairment in occupational
functioning or in usual social activities or
In children and adolescents, the mood may be
Not due to substance use or abuse, or a general
Lasting consistently for at least 2 weeks.
Represents a significant change from previous
After the loss of a loved one, the symptoms persist for longer than 2 months or are characterized by marked functional impairment, morbid preoccupation with worthlessness, suicidal ideation, psychotic symptoms, or psychomotor retardation
Diagnosis: Major Depressive Symptoms at School
Major Depressive Episode Criteria (cont.)
Five or more of the following symptoms (at least one of
Depressed Mood: Feels or looks Markedly Diminished Interest or Pleasure in All Activities: Significant Weight Loss/Gain or Appetite Increase/Decrease:
7) Feelings of worthlessness/inappropriate guilt
8) Diminished ability to think or concentrate/indecisiveness
From Lofthouse & Fristad (2006, p. 216)
Diagnosis: Major Depressive Symptoms at School
Diagnosis: Major Depressive Symptoms at School
Insomnia or Hypersomnia: Low Self-Esteem, Feelings of Worthlessness or Excessive Guilt: Thinking and saying more no one likes me, I can’t do anything.” Psychomotor Agitation/Retardation: Looks Diminished Ability to Think or A child can’t seem to focus in class, Concentrate, or Fatigue or Loss of Energy: Indecisiveness: Increase
baseline attentional capacity; difficulty stringing thoughts together or making choices.
From Lofthouse & Fristad (2006, p. 216)
From Lofthouse & Fristad (2006, p. 216)
Diagnosis: Major Depressive Symptoms at School
Hopelessness: Negative
Both Manic and Major Depressive Episode criteria are
met nearly every day for a least a 1 week period.
Recurrent Thoughts of Death
Rapidly alternating moods (sadness, irritability, euphoria) accompanied by symptoms of a Manic and
or Suicidality: Obsession with
Causes marked impairment in occupational functioning
or in usual social activities or relationships, or
Necessitates hospitalization to prevent harm to self or
others, or
possessions away or tries to kill self.
Not due to substance use or abuse, or a general medical condition
From Lofthouse & Fristad (2006, p. 216)
Terms used to define juvenile bipolar disorder.
Ultrarapid cycling = 5 to 364 episodes/year
Four or more mood episodes (i.e., Major Depressive, Manic, Mixed, or Hypomanic) per 12 months
Brief frequent manic episodes lasting hours to days, but less than the 4-days required under Hypomania
a period of full remission, or
Ultradian cycling = >365 episodes/year
a switch to an episode of the opposite polarity
Repeated brief cycles lasting minutes to hours (77%).
Manic, Hypomanic, and Mixed are on the same pole
Chronic baseline mania (Wozniak et al., 1995).
Ultradian is Latin for “many times per day.”
NOTE: This definition is different from that used in some literature, where in cycling refers to mood changes within an episode (Geller et al., 2004).
Mania includes marked euphoria, grandiosity, and irritability
Racing thoughts, increased psychomotor activity, and mood lability.
Discrete episodes of mania or depression lasting
Mania is frequently associated with psychosis, mood lability, and depression.
Tends to be more chronic and difficult to treat than adult BPD.
Significant departures from baseline functioning.
Prognosis similar to worse than adult BPD
Mania involves markedly labile/erratic changes in mood, energy levels, and behavior.
Predominant mood is VERY severe irritability (often associated with
Irritability, anger, belligerence, depression, and mixed features are
Lower rates of inter-episode recovery.
Mania is commonly mixed with depression.
AACAP (2007); NIMH (2001); Wozniak et al. (1995)
Unique Features of Pediatric Bipolar Disorder
Bipolar Disorder in childhood and adolescence appear to
However, there are significant developmental variations
Predominantly mixed episodes (20% to 84%) and/or
High rate of comorbid ADHD (75% to 98%) and
Increased thirst, increased urination, water retention
Brain-Derived Neurotropic Factor (BDNF) & Apoptosis
Electro-Convulsive Therapy (ECT) & Repeated
Multifamily Psycho-education Groups (MFPG)
Transcranial Magnetic Stimulation (r-TMS)
Interpersonal and Social Rhythm Therapy (IPSRT)
Best Practices for School Psychologists
Adolescent onset = significant disruptions
Develop the Psycho-Educational Assessment
Understand the focus of the assessment Eligibility Category?
Special Education Eligibility Categories
An inability to learn that cannot be explained by other
An inability to build or maintain satisfactory
interpersonal relationships with peers and teachers.
Inappropriate types of behavior or feelings under
A general pervasive mood of unhappiness or
A tendency to develop physical symptoms or fears
associated with personal or school problems.
Having limited strength, vitality, or alertness,
including a heightened alertness to environmental
stimuli, that results in limited alertness with
respect to the educational environment that:
is due to chronic or acute health problems such as
asthma, attention deficit disorder or attention deficit
Represents the origin of the
hyperactivity disorder, diabetes, epilepsy, a heart
presentation of the disorder.
condition, hemophilia, lead poisoning, leukemia, nephritis, rheumatic fever, and sickle cell anemia; and
adversely affects a child’s educational performance.
Any medical conditions that may be impacting
Child-Behavior Checklist (CBCL) Behavior Assessment System for Children (BASC-II)
Devereux Scales of Mental Disorders (DSMD)
What type of information will you be collecting?
Mania Washington University in St. Louis Kiddie Schedule for Affective Disorders and Schizophrenia (WASH-U KSADS)
Young Mania Rating Scale General Behavior Inventory (GBI)
Questionnaires, phone calls, or face-to-face?
Depression Beck Depression Inventory (BDI) Hamilton Rating Scale for Depression Reynolds Adolescent Depression Scale (RADS-2)
Socio-Emotional Functioning, cont.
Woodcock-Johnson Tests of Cognitive Abilities (WJ-III)
Brown Attention-Deficit Disorder Scales for Children and
Wechsler Intelligence Scale for Children (WISC-IV)
Developmental Neuropsychological Assessment (NEPSY)
Scale for Assessing Emotional Disturbance (SAED)
Kaufman Assessment Battery for Children (KABC-2)
Differential Ability Scales (DAS-2)
Revised Children’s Manifest Anxiety Scale (RCMAS)
Wide Range Assessment of Memory & Learning (WRAML-2)
Behavior Rating Inventory of Executive FunctionsComprehensive Test of Phonological Processing (CTOPP)
Comprehensive Behavior Rating Scale for ChildrenTests of Auditory Processing (TAPS-3)
Motor-Free Visual Perception Test (MVPT-3)
Delis-Kaplan Executive Function ScaleBeery Buktenica Developmental Test of Visual Motor-Integration (VMI)
Conners Continuous Performance TestBender Visual-Motor Gestalt Test (Bender-Gestalt II)
Special Education & Programming Issues
Background (e.g., developmental, health, family, educational)
Socio-Emotional Functioning (including rating scales, observations, interviews, and narrative descriptions)
Cognitive Functioning (including Executive Functions & Processing Areas)
Special Education & Programming Issues
Special Education & Programming Issues
Medi-Cal/Access to mental health services
Special Education & Programming Issues
Questions to ask when developing a plan:
What are the student’s particular challenges?
Will it be part of the IEP as a Designated Instructional Service (DIS)?
What does the student need in order to get
Is student’s behavior impeding access to his/her
Possible elements of a counseling program
Build, maintain, and educate the school-based
Provide a predictable, positive, and flexible
Be aware of and manage medication side effects.
Be prepared for episodes of intense emotion.
Consider alternatives to regular classroom.
Lofthouse & Fristad (2006, pp. 220-221)
Best Practices for School Psychologists
¾ Provide books on tape and/or reading partners
¾ Don’t punish or single out for sleepiness
Account for Impaired Concentration, Focus, and Memory
Provide assistance for missed assignments
Allow students to work in calm environments
Don’t allow student to be the focus of attention
The Storm in my Brain A publication from the Child & Adolescent Bipolar Foundation (CABF). Artwork for this booklet was created by
young people living with depression or bipolar disorder. These works were selected from over 100 entries to a national contest
sponsored by DBSA and CABF. This is an easy to understand,
colorful booklet that speaks to children about how it feels to have a mood disorder. http://www.bpkids.org/site/PageServer?pagename=lrn_books_children
The Bipolar Child by Demitri Papolos, M.D.
http://www.bpkids.org/site/PageServer?pagename
and Janice Papolos (Broadway Books, 2006).
Educational brochure: Educating the Child
http://www.bpkids.org/site/DocServer/edbrochure. With effective treatment, you can live an enjoyable and productive life
AACAP. (2007). Practice parameter for the assessment and treatment of children
despite bipolar disorder.
and adolescents with bipolar disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 46, 107-125.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., Text Rev). Washington, DC: Author.
Baum, A. E., Akula, N., Cabanero, M., Cardona, I., Corona, W., Klemens, B.,
Schulze, T. G., Cichon, S., Rietsche, l. M., Nöthen, M. M., Georgi, A.,
Schumacher, J., Schwarz, M., Abou Jamra, R., Höfels, S., Propping, P.,
Satagopan, J., Detera-Wadleigh, S. D., Hardy, J., & McMahon, F. J. (2007).
A genome-wide association study implicates diacylglycerol kinase eta
(DGKH) and several other genes in the etiology of bipolar disorder. Molecular Psychiatry, [E-pub ahead of print].
Danielyan, A., Pathak, S., Kowatch, R. A., Arszman, S. P., & Jones, E. S. (2007).
Clinical characteristics of bipolar disorder in very young children. Journal of Affective Disorders, 97, 51-59.
Faraone, S. V., Glatt, S. J., & Tsuang, M. T. (2003). The genetics of pediatric-
onset bipolar disorder. Biological Psychiatry, 53, 970-977.
The biographies of Beethoven, Newton, and Dickens, in
Geller, B., Tillman, R., Craney, J. L., & Bolhofner, K. (2004). Four-year
particular, reveal severe and debilitating recurrent mood
prospective outcome and natural history of mania in children with a prepubertal and early adolescent bipolar disorder phenotype. Archives of General Psychiatry, 61, 459-467.
Geller, B., Williams, M., Zimerman, B., Frazier, J., Beringer, L., & Warner, K. L.
Massachusetts General Hospital (2008). School Psychiatry Program & Madi
(1998). Prepubertal and early adolescent bipolarity differentiate from ADHD
by manic symptoms, grandiose delusions, ultra-rapid or ultradian cycling.
http://www.massgeneral.org/schoolpsychiatry/interventions_begin.asp
Journal of Affective Disorders, 51, 81-91.
Mayo Clinic (2008). Bipolar Disorder retrieved from
Hajek, T., Carrey, N., & Alda, M. (2005). Neuroanatomical abnormalities as risk
factors for bipolar disorder. Bipolar Disorders, 7, 393-403.
http://www.mayoclinic.com/health/bipolar-disorder/DS00356
Indianapolis Bipolar Parents Organization (2005, April). Helping children with
NIMH. (2001). National Institute of Mental Health research roundtable on prepubertal
early-onset pipolar to learn. Retrieved March 5, 2005, from
biopolar disorder. Journal of the American Academy of Child & Adolescent Psychiatry,
www.indplsbpparents.org/CABF_BPchildlearning.PDF
Indianapolis Bipolar Parents Organization (2005, April). Resource guide for
NIMH. (2007). Bipolar disorder. Bethesda, MD: Author. Retrieved May 28, 2007, from
parents of biopolar children. Retrieved March 5, 2005, from
http://www.nimh.nih.gov/publicat/bipolar.cfm
http://www.indplsbpparents.org/Resource.pdf
Pavuluri, M. N., Birmaher, B., & Naylor, M. W. (2005). Pediatric bipolar disorder: A review of
the past 10 years. Journal of the American Academy of Child and Adolescent
Lofthouse, N. L., & Fristad, M. A. (2006). Bipolar disorders. In G. G. Bear & K. M.
Minke (Eds.) Children’s needs III: Development, prevention, and intervention
Wozniak, J., Biederman, J., Kiely, K., Ablon, J. S., Faraone, S. V., Mundy, E., & Mennin, D.
(pp. 211-224). Bethesda, MD: National Association of School Psychologists.
(1995). Mania-like symptoms suggestive of childhood-onset bipolar disorder in
Masi, G., Perugi, G., Millepiedi, S., Mucci, M., Toni, C., Bertini, N., Pfanner, C.,
clinically referred children. Journal of the American Academy of Child & Adolescent
Berloffa, S., & Pari, C. (2006). Developmental difference according to age at
onset in juvenile bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 16, 679-685.
Delia Villasenor, Stephen Brock, & Beth Hopper
MANAGEMENT VON GEMISCHTER CALCIUMOXALAT- UND STRUVIT- UROLITHIASIS BEI ADULTEN KATZEN Dies ist nicht unüblich bei Katzen. Diätetisches Management Es ist so, dass das primäre Problem eine Prädisposition für Calciumoxalatbildung ist, mit sekundärer Struvitbildung nach einer Harnwegsinfektion mit ureaseproduzierenden Organismen, speziell bei über sieben Jahre alten Persern, Him
Nel transfer pricing, analisi di comparabilità in base al caso concreto La Suprema Corte canadese ha stabilito che, nella determinazione dei prezzi di trasferimento, è necessario considerare l’effettiva realtà economica / Piergiorgio VALENTE Nel periodo 1990-1993, la società farmaceutica canadeseto quanto deciso dalla Corte Federale di Appello e rimessoGlaxoSmithKline Inc. (di se