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Kadikoy Maarif College (American College), Istanbul
Faculty of Medicine, University of Istanbul, Turkey
Curriculum Vitae Dr Bulend Yuksel Page 1
Medical Faculty Graduate (with distinction)
Accredited as specialist in Paediatrics following an exit
examination, Istanbul - Turkey (CCST equivalent)
Accredited as Associate Professor in Paediatrics following a board
examination and a viva (Docent) - University of Istanbul.
Fellow of Royal College of Physicians of Ireland
Fellow of Royal College of Paediatrics and Child Health
Aetiology, investigation and treatment of respiratory morbidity following premature
birth. Phd finished, papers published, Writing of the Thesis not completed after
Curriculum Vitae Dr Bulend Yuksel Page 2
Chase Farm and Barnet Hospitals NHS Trust, Enfield/Barnet - London
Interests; Perinatology, Neonatology and Paediatric Respiratory
Honorary Senior Lecturer at University College London Medical School
Undergraduate Tutor – Barnet and Chase Farm Hospitals NHS Trust
Clinical Research Fellow - Registrar, Hon Senior Registrar
King’s Col ege School of Medicine and Dentistry.
Summary of previous appointments:
Istanbul Medical Faculty Hospital SHO - 6 Months
King’s Col ege Hospital, London, Middle Grade On-call rota, (5 years)
Istanbul Medical Faculty Hospital SHO - 2.5 Years,
King’s Col ege Hospital - London Middle Grade, On-call rota, (3 years)
Curriculum Vitae Dr Bulend Yuksel Page 3
I teach Medical Students, Nursing Staff and junior doctors during my regular ward rounds.
a) Appointed as Undergraduate Tutor
for the Barnet and Chase Farm Hospitals (2001)
b) Regular teaching of Medical students, organising the first Revision course for the Year
5 medical students of Royal Free and UCLH at Chase Farm Hospital.
c) Regular bedside teaching of medical students at Medical Faculty Hospital-Istanbul,
Whittington Hospital, King’s Col ege Hospital and Chase Farm Hospital.
d) Lectures to medical and nursing students.
e) Priviously, Neonatology lectures to University College London Medical School students
in the Paediatric Consolidation Course at UCLH.
a) Regular teaching for DCH (Pastest)-London twice yearly.
b) Regular Membership (written and clinical) and DCH teaching for junior Paediatric staff
c) Regular weekly half day teaching sessions for Paediatric SHO’s.
d) Induction teaching sessions to new Paediatric SHO’s and separately to A/E SHO’s.
e) Regular lectures and demonstrations of new techniques (i.e. HFOV, NO administration)
for the Neonatal Nurses and other Neonatal team members.
a) Series of Neonatal lectures at the University of Istanbul (1993).
b) Stoke Mandeville Hospital, Neonatal Study day: Respiratory morbidity of VLBW infants
c) International Neonatology days - Istanbul: VLBW infants and respiratory problems in
d) Harlow Hospital: Recurrent respiratory problems of ex-premature infants at follow-up
e) Maidstone Hospital: Investigation and treatment of respiratory morbidity following
f) Chase Farm Hospital Postgraduate Centre: Management of wheezy pre-school children
Curriculum Vitae Dr Bulend Yuksel Page 4
g) Royal College of Physicians-London: Resuscitation of the Newborn-Evidence based
practice. Panel member and speaker (8th October 1997).
h) North London Postordination training day-London: Death around the time of birth;
Caring for premature and sick babies-Neonatal Death (21st January 1998).
h) Royal Pharmaceutical Society-London: Care of sick and premature newborns in the
hospital and community; implications for drug therapy following discharge (9th March
i) Chase Farm Hospital Neonatal Study Day: Continuing respiratory morbidity, and its
management following Neonatal IntensiveCare ( 26th June 1998, 1999 and 2000).
j) Chase Farm Hospital Paediatric Surveillance Course: Diagnosis and Management of
Pre-school asthma (13th July 1998, 1999, 2000 and 2001).
k) Queen Elizabeth II and Lister Hospitals: Pathophysiology of Neonatal Chronic Lung
l) CFH Postgraduate Centre: The effects of smoking on children from womb to tomb,
m) CFH Postgraduate Centre: The nutrition of the SCBU/NICU graduated at home, Study
Day for Dietitians and Community Health Workers, 1999
n) Neonatal Advanced Life Support Course - Lister Hospital: Course instructor and
lecturer (March 1999). PALS and NALS instructor and lecturer, Royal Free, St
Georges Hospital, Lister Hospital and Scotland NALS -1999 to 2002.
o) Organised and lectured Evening Paediatric Respiratory Meetings for Trainees and
Specialist Nurses; Preschool wheezing, February 1999, Asthma in young children June
1999, Meconium Aspiration Syndrome, respiratory morbidity at follow-up and treatment,
November 1999, Paediatric Asthma past and present, October 2000.
p) Chase Farm Hospital Neonatal Study Day: Management of Meconium Aspiration
q) Organising and lecturing one day teaching in "Educating towards Clinical Governance":
Module one – Critical analysis of data and evidence and its use in making clinical
decisions, at Barnet and Chase Farm Hospital NHS Trust. March 2001, October 2001,
Curriculum Vitae Dr Bulend Yuksel Page 5
r) CFH Postgraduate Centre: Common Respiratory Problems in Children, September
s) Evening GP teaching and lectures: Childhood/Adolescent asthma, Management of
Asthma in young, Asthma management – expectations and the reality. March 2001,
t) International Millenium Paediatric Respiratory Diseases Meeting (Dublin/Ireland) –
Respiratory Diseases of Neonates, March 2000.
u) Southern Paediatric Annual Respiratory Conference (Dublin /Ireland) – The effects of
Cigarette Smoking on Children, March 2001.
v) European Society for the Study and Prevention of Infant Death (ESPID,
Istanbul/Turkey) – a) Prevention of SIDS/Personal experience in UK and Turkey b)
Effects of smoking on Sudden Infant Death Syndrome. October 2001
MEMBERSHIP OF MEDICAL & SCIENTIFIC RESEARCH SOCIETIES:
British Association of Perinatal Medicine
Paediatric Research Society – currently retired as I am above 50 years of age
British Paediatric Immunology and Infectious Diseases Group
American Thoracic Society – Member for 18 years
European Respiratory Society (Secretary and later Chair
for the NICU and PICU
Scientific Group for 7 years), currently GOLD MEMBER ( Member more than 20 years)
Curriculum Vitae Dr Bulend Yuksel Page 6
Joint Research Committee of King’s Col ege Hospital (JRC)
Publications in the UK:
B Yuksel, A Greenough, I Maconochie, Effective bronchodilator therapy by a simple
spacer device for wheezy premature infants in the first two years of life. Arch Dis
A Greenough, I Maconochie, B Yuksel, Recurrent respiratory symptoms in the first year of
life following preterm delivery. J Perinat Med 1990;18:489-494
MD Smith, C Worman, F Yuksel, B Yuksel, L Moretta, E Ciccone, CE Grossi, L
Mackenzie, PM Lydyard, T cell subsets in cord and adult blood. Scan J Immunol
B Yuksel, A Greenough, S. Green, Lung function abnormalities at six months of age
following neonatal intensive care. Arch Dis Child 1991;66:472-476
Curriculum Vitae Dr Bulend Yuksel Page 7
B Yuksel, A Greenough, Effect of nebulised Salbutamol in preterm infants during first year
of life. Eur Res J 1991;4:1088-1092 (included in current world literature for Current Opinion
in Pediatrics, 1993, edited by DG Nathan and FA Oski)
B Yuksel, A Greenough, Relationship of symptoms to lung function abnormalities in
preterm infants at follow-up. Pediatr Pulmonol 1991;11:202-206 (abstracted in the Year
Book of Neonatal and Perinatal Medicine, Mosby-Year Inc. 1992)
B Yuksel, A Greenough, S Green, Paradoxical response to nebulised ipratropium bromide
in asymptomatic preterm infants . Res Med 1991;85:189-194 (abstracted in Pediatrics
Digest-Neonatology, Clinical Digest Series, Northbrook IL, USA, 1991)
B Yuksel, A Greenough, Neonatal respiratory distress and lung function at follow-up. Res
B Yuksel, A Greenough, Ipratropium bromide in symptomatic preterm infants.
B Yuksel, A Greenough, J Karani, A Page, Chest radiograph scoring system for use in
pre-term infants . Br J Radiol 1991;64:1015-1018
I Machonichie, A Greenough, B Yuksel, A Page, J Karani. A chest radiograph scoring
system to predict chronic oxygen dependency in low birth weight infants. Early Hum Dev
RA Mageed, LE Mackenzie, FK Stevenson, B Yuksel, F Shokril, BR Maziak, R Jefferis,
PM Lydyard. Selective expression of cross-reactive idiotype characteristic of a subfamily
within the VHIV subfamily of immunoglobulin genes in human CD5+ B lymphocytes from
LE Mackenzie, RA Mageed, PY Youinou, B Yuksel, R Jefferis, PM Lydyard, Auto and
polyreactivity of IgM from CD5+ and CD5- cord blood B cells. Scan J Immunol
B Yuksel, A Greenough, Persistence of respiratory symptoms into the second year of life:
predictive factors in infants born preterm. Acta Paediatr Scan 1992;81:832-835
Curriculum Vitae Dr Bulend Yuksel Page 8
B Yuksel, A Greenough, Lung function in 6-20 month old infants born very preterm but
without respiratory troubles. Pediatr Pulmonol 1992;14:214-221
B Yuksel, A Greenough, J Karani, Comparison of subjective and quantitative assessment
of the neonatal chest radiograph appearance. Br J Radiol 1992;65:1083-1085
B Yuksel, A Greenough, Neonatal respiratory support and lung function abnormalities at
B Yuksel, A Greenough, Acute deteriorations in neonatal chronic lung disease. E J
B Yuksel, A Greenough, Randomised trial of prophylaxis by inhaled steroids in preterm
infants symptomatic at follow-up. Thorax 1992;47:910-913
B Yuksel, A Greenough, Inhaled Sodium Cromoglycate for infants preterm symptomatic at
B Yuksel, A Greenough, Lung function abnormalities and their treatment in preterm
infants following discharge from neonatal intensive care. Turk J Med Biol Res (Review)
FM Erkeller-Yuksel, V Deneys, B Yuksel, F Hulstaert, C Hamilton, H Mackinnon, L Turner-
Stokes, L Mackenzie, D Latinne, V Munhyehuli, C Grard, J Lowder, F Vanlengendonk, M
DeSilva, M DeBruyere, T Reichert, PM Lydyard, Age related changes in human
lymphocyte subpopulations. J of Pediatr 1992;120:216-222.
LE MacKenzie, RA Mageed, PY Youinou, B Yuksel, R Jefferis, PM Lydyard. Repertoire of
CD5+ and CD- cord blood B cells: Specificity and expression of VHl and VHIII associated
idiotypes. Clin Exp Immunol 1992;88:107-111
B Yuksel, A Greenough, V Chan, R Russel, Comparison of helium dilution and nitrogen
washout measurements of functional residual capacity in premature infants. Ped Pulmonol
Curriculum Vitae Dr Bulend Yuksel Page 9
B Yuksel, A Greenough, Nebulised sodium cromoglycate in preterm infants - protection
against water challenge-induced bronchoconstriction. Res Med 1993;87:37-42
B Yuksel, A Greenough, H Gamsu, Respiratory function at follow-up after neonatal
surfactant replacement therapy. Res Med 1993;87:217-221(abstracted in Pediatrics
Digest, Clinical Digest Series, Northbrook IL, USA 1993)
B Yuksel, A Greenough, The effect of sodium cromoglycate on upper-lower respiratory
symptoms in children born prematurely. Eur J Pediatr 1993;152:615-618
B Yuksel, A Greenough, Variable response to bronchodilator therapy in children born
B Yuksel, A Greenough, Effect of exogenous surfactant replacement therapy on lung
function. Turk J Pediatr (Review) 1993;35: Jan-March, 53-57
A Greenough, B Yuksel, L Everett, JF Price, Inhaled ipratropium bromide and terbutaline
in asthmatic children. Res Med 1993; 87: 111-114
L Emery, A Greenough, B Yuksel, Effect of gender on blood pressure levels of very low
birth weight infants in the first 48 hours of life. Early Human Dev 1993; 31: 209-216
B Yuksel, A Greenough, J Karani, Prediction of chronic lung disease from the chest
radiograph appearance at 7 days of age. Acta Paed Scan 1993; 82: 944-947
B Yuksel, A Greenough, H R Gamsu, Neonatal meconium aspiration syndrome and
respiratory morbidity during infancy. Ped Pulmonol 1993; 16: 358-361
B Yuksel, A Greenough, Viral infections acquired during neonatal intensive care and lung
function of preterm infants at follow-up. Acta Paed Scan 1994; 83: 117-118
A Greenough, B Yuksel, KH Nicholaides, Abnormalities of lung volume at follow-up after
antenatal rhesus iso-immunisation. Acta Paed Scan 1994; 83: 498-500
F Giffin, A Greenough, B Yuksel, Does the duration of oxygen dependence after birth
influence subsequent respiratory morbidity? Eur J Pediatr 1994; 153: 34-37
Curriculum Vitae Dr Bulend Yuksel Page 10
F Giffin, A Greenough, B Yuksel, Prediction of respiratory morbidity in the third year of life
in children born prematurely Acta Paed Scan 1994; 83: 157-158
B Yuksel, A Greenough, Birth weight and hospital re-admission of infants born
prematurely. Arch Pediatr Adolesc Med 1994;148: 384-388 (Formerly Am J Dis Child).
B Yuksel, A Greenough, Influence of lung function and postnatal age on the response of
nebulised Ipratropium bromide in children born prematurely. Resp Med 1994; 88: 527-30
B Yuksel, A Greenough, Comparison of the effects on lung function of two methods of
bronchodilator administration. Res Med 1994; 88: 229-233.
B Yuksel, A Greenough, Airway resistance and lung volume before and after
bronchodilator therapy in symptomatic preterm infants. Res Med 1994; 88: 281-286.
B Yuksel, A Greenough, Glucocorticoids (Letter). Acta Paed Scan 1994; 83: 342
F Giffin, A Greenough, B Yuksel, Relationship of lung function results in the first year of
life and respiratory morbidity in early childhood in patients born prematurely. Ped
B Yuksel, A Greenough, Measurement of thoracic gas volume in patients born
prematurely-should occlusion be made at end inspiration or end expiration. Ped Pulmonol
B Yuksel, A Greenough, KH Nicolaides, Functional residual capacity to thoracic gas
volume (FRC/TGV) ratio in healthy neonates. Res Med 1995; 89:429-433
F Giffin, A Greenough, B Yuksel, Does a family history of atopy influence lung function at
follow-up of infants born prematurely? Acta Paed Scan 1995; 84:17-21
F Giffin, A Greenough, B Yuksel, Antiviral therapy in neonatal chronic lung disease. Earl
Curriculum Vitae Dr Bulend Yuksel Page 11
B Yuksel, A Greenough, Ethnic origins and lung function of infants born prematurely.
B Yuksel, A Greenough, F Giffin, KH Nicolaides Tidal breathing parameters in the first
week of life and subsequent cough and wheeze. Thorax 1996; 51: 815-818
M Maeda, R Von Schae, B Yuksel, A Greenough, MW Fanser, PM Guyrie, P Lydyard,
Differential expression of Fc receptors for IgG by monocytes and granulocyts from
neonates and adults. Clin Exp Immunol 1996;103:343-347
B Yuksel, A Greenough, P Dopson, K H Nicholaides, Advanced maternal age and
smoking: risk factors for admission to a neonatal intensive care unit . J Perinat Med 1996;
A Greenough, F Griffin, B Yuksel, Respiratory morbidity in preschool children born
prematurely. Relationship to adverse neonatal events Acta Paediatr 1996; 85: 772-777
A Greenough, F Giffin, B Yuksel, G Dimitriou, Respiratory morbidity in young school
children born prematurely - Chronic Lung Disease is not a risk factor? Eur J Paediatr
B Yuksel, A Greenough, Inhaled Nedocromil Sodium and symptomatic young children
born prematurely. Res Med 1996 ;90: 467-471
A J Cook, B Yuksel, A Greenough, PJ Piper, JF Price, Evidence for the involvement of
Leukotrienes in chronic lung disease of infancy. Eur Res J 1996; 9: 1907-1912
B Yuksel, A Greenough, S Naik, KH Nicholaides, Perinatal lung function and invasive
antenatal procedures. Thorax 1997; 52: 181-184
A Greenough, B Yuksel, S Naik, P Cheeseman, KH Nicholaides, First trimester invasive
procedures: Effects on symptom status and lung volume in very young children. Pediatr
A Greenough, S Naik, B Yuksel, PJ Thompson, KH Nicholaides, First trimester invasive
procedures and congenital abnormalities. Acta Paediatrica 1997; 86:1220-1223
Curriculum Vitae Dr Bulend Yuksel Page 12
A Greenough, F Giffin, G Dimitriou, B Yuksel, Risk factors for hyperinflation in young
school children born prematurely. Eur J Pediatr 1997; 156: 148-151.
A Greenough, B Yuksel, S Naik, P Cheeseman, KH Nicholaides, Invasive antenatal
procedures and requirement for neonatal intensive care unit admission. Eur J Pediatr
B Yuksel, Long term effects of RSV Bronchiolitis. Respiratory exchange (Review),
A Greenough, Y-K Zhang, B Yuksel, G Dimitriou, Assessment of prematurely born
children at follow-up using a tidal breathing parameter, Physiol. Measur. 1998;19: 111-116
AF Brady, PP Pandya, B Yuksel, A Greenough, MA Patton, KH Nicholaides, Outcome of
chromosomally normal livebirths with increased fetal nuchal translucency at 10-14 weeks
gestation. Journal of Medical Genetics 1998; 35: 3222-4.
A Greenough, S Naik, Y Itakura, B Yuksel, KH Nicolaides, Perinatal lung function
measurements and prediction of respiratory morbidity in infancy. Physiological
P B Munroe, R Olgunturk, J P Fryns, L V Maldergem, F Ziereisen, B Yuksel, R M Gardiner
and E Chung, Mutations in human matrix Gla protein gene, MGP cause Keutel
Syndrome. Nature Genetics 1999; 21: 142-144.
M Kinali, A Greenough, G Dimitriou, B Yuksel, R Hooper, Chronic Respiratory morbidity
following premature delivery - prediction by prolonged respiratory support requirement ?,
J Fincham, P P Pandya, B Yuksel, Y M Loong, J Shah, Increased first-trimester nuchal
translucency as a prenatal manifestation of salt-wasting congenital adrenal hyperplasia,
Ultrasound Obstetric Gynecol 2002; 20: 392-394
Curriculum Vitae Dr Bulend Yuksel Page 13
Joint British Paediatric Respiratory group-Fisons pharmaceuticals; Travel
For attending American Lung Association-American Thoracic Society
Paediatric Research Society Travel Award, 1993:
For attending the Pediatric Flexible
Bronchoscopy Course at the University of North Carolina, USA. August 1994.
Glaxo Wellcome Medical Fellowship, 1998
(award for £3600.00): For purchasing an
infant knemometer and employing staff to conduct a project at Chase Farm Hospital.
Sports; I was the captain of the Medical Faculty football team at the University. I take part
regular competitive swimming and tennis. I also do basketball, snowboarding/skiing,
Curriculum Vitae Dr Bulend Yuksel Page 14
Diuretics and Drugs Affecting Renal Function, Water, and Electrolyte Metabolism Subcommittee: Strandhoy, Jack W., Chair, [email protected] Jeffries, William B. Diuretics Recommended Curriculum Equivalent: 2 hrs Drug Classes and Drugs to Consider Learning Objectives Physiology and Pathophysiology Describe the location and function of major ion transporters and ch
ORIGINAL CONTRIBUTIONS Reproducibility of Multichannel Intraluminal ElectricalImpedance Monitoring of Gastroesophageal RefluxAlbert J. Bredenoord, M.D., Bas L.A.M. Weusten, M.D., Ph.D., Robin Timmer, M.D., Ph.D.,and Andre J.P.M. Smout, M.D., Ph.D. Department of Gastroenterology, Sint Antonius Hospital, Nieuwegein; and Gastrointestinal Research Unit,University Medical Center, Utrecht, The Nethe