Microsoft word - sup_acetylcarnitine
Acetylcarnitine; also called Acetyl-l-carnitine or ALCAR
D E S C R I P T I O N :
is a form of carnitine
(also known as L-carnitine
) is an amino acid derivative
synthesized from lysine
. It is found in nearly all cells of the body. Produced in the liver and kidneys, it
is stored in the skeletal muscles, heart, brain, and sperm.
Carnitine, found in the muscles,
is involved in transferring fatty acids
across mitochondrial membranes
; fatty acids are burned in the mitochondria to produce energy.
component of acetylcarnitine
provides for the formation of the neurotransmitter
; acetylcholine deficits in certain brain regions are thought to be associated with age-related dementias, including Alzheimer's disease.
is often regarded as the preferred form for carnitine
because it is better absorbed
from the small intestine than L-carnitine
and more efficiently
crosses the blood-brain barrier
F U N C T I O N :
may have a triglyceride-lowering effect
for some people, as well as
helping to elevate HDL (“good”) cholesterol
levels. It may have cardioprotective
addition to beneficially affecting cardiac function
. It may also have antioxidant
There has been a great deal of attention to carnitine
because it may help counter the
experienced in HIV infection and all the successive problems which
that may cause, including neuropathy, myopathy, bone marrow suppression (and resulting
decreases in red and white blood cells and platelets), pancreatitis, fatty liver, lactic acidosis,
and fat loss (lipoatrophy).
has also been used as a “smart drug” to enhance memory
and other cognitive functions
S O U R C E S :
are: red meats, with lesser amounts found in fish,
poultry, and milk products. Small amounts are also found in wheat and avocados.
Recommended dosages range from 500mg …1000mg …2000mg per day.
A 2009 report on acetylcarnitine
used in a pilot study of people with elevated cardiovascular
disease risk found significant improvement in high blood pressure and glucose control among
the study subjects.
Long-term studies of acetylcarnitine
suggest that it can help damaged nerves recover from
the toxicity of certain anti-HIV drugs such as d4T (Zerit, stavudine) and ddI (Videx EC,
didanosine). In particular, acetylcarnitine
has shown benefit in reducing diabetes risk and
peripheral neuropathy symptoms in people with HIV.
is a major component of Dr. Jon Kaiser’s micronutrient supplementation
package, which (as reported in a 2006 study) produced an increase in CD4 counts in people
with HIV on HAART. NYBC subsequently developed a low-cost near equivalent to K-PAX®,
which actually provides more acetylcarnitine
than the original Jon Kaiser formula.
(Montiff) Each bottle, 100 capsules. Each capsule, 500 mg of N-acetyl-L-
P R O D U C T S :
, a form of the amino acid derivative, carnitine
(Jarrow/Biosint) Each bottle, 120 veggie capsules. Each capsule, 500
mg of acetyl-L-carnitine from Biosint, a trademark of Sigma-Tau Industries, S.p.A, in Rome,
Italy. This Italian product has been used in many research studies.
supplements should be kept refrigerated
to maintain potency.
Month / Year: Time Point: STUDENT FOOD LABEL QUIZ For each of the following pairs of foods in the same food category, such as bread or cereal or crackers or cookies, choose the one you think is more nutritious (“better for you”) by filling in th bubble next to your choice. Please use a #2 pencil. To change your answer, erase completely. 1. FOOD CATEGORY: CRACKERS Amount Pe
Food and Chemical Toxicology 40 (2002) 1263–1270Eﬀects of caﬀeine on bone and the calcium economyCreighton University, 2500 California Plaza, Omaha 68178 Nebraska, USACaﬀeine-containing beverage consumption has been reported to be associated with reduced bone mass and increased fracture riskin some,but not most,observational studies. Human physiological studies and controlled balan