May 4, 2005 Volume 4, Issue 1
limiting the local transmission of M. tuberculosis, such as case finding and treatment until cure, prompt
Palm Beach County
contact investigations, identification and treatment of
infected contacts, and the use of appropriate anti-tuberculosis treatment under Directly Observed
Tuberculosis Annual
In 2004, several initiatives to improve management
and services provided to TB patients were
implemented countywide to ensure continuity of care and TB prevention. In 2005, new initiatives are being
carried out to improve service delivery, partnership, and outreach to high-risk groups.
Many people think that tuberculosis (TB) is a disease
of the past-an illness that no longer threatens us
Boubker Naouri, M.D., M.P.H.
today. However, with one third of the world's
Tuberculosis Control Program Manager
population estimated to be infected with the bacteria
Palm Beach County Health Department
that cause TB, this ancient disease is very much with
us today. Among infectious diseases, TB remains the
second leading killer in the world, with more than 2
In 2004, PBC reported 99 TB cases with a case rate of 7.9 per 100,000 (Figure I). This represents 9% of all TB
This annual report describes the distribution of TB
cases among the population of Palm Beach County
(PBC). A total of 99 TB cases were reported during 2004 in PBC, an increase of 13% compared to 2003.
Figure I. TB cases and rates, Palm Beach, FL, 1993-2004
This increase is partially the result of two factors:
Immigration from countries with high prevalence of TB
In 2004, 64% of TB cases recorded in PBC were
among foreign-born compared to 42% in 2003.
HIV/AIDS epidemic
TB and HIV co-infection rate in PBC (27%) is 66%
higher than the co-infection rate in the State of
To meet these challenges, PBC Tuberculosis Control
Program will keep focusing on control measures
Palm Beach County Health Department, Broadway Health Center TB Control Program
Phone: (561) 882-3110 Fax: (561) 845-4468 E-mail: [email protected]Figure IV. TB Foreign-born cases by country of origin, Palm
Eighty-one percent of 2004 TB cases were male.
Beach, FL, 2004
Children ages 0 to 10 years accounted for 1% of cases
(Figure II). The median age of TB cases was 44.5
years and ranged from 1 to 91 years of age. Persons
Honduras
aged 41 to 50 made up the largest group of TB cases,
Guatemala Figure II. TB counted cases by age groups, Palm Beach, Florida 2004
The proportion of the co-infection with HIV among
TB cases recorded in 2004 was 27%, followed by
excess of alcohol (22%) and non-injection drug use
Figure V. TB cases by risk factors, Palm Beach, Florida, 2004
The distribution of TB cases in PBC by race/ethnicity in 2004 was 32% Hispanic, 44% Black/Non-Hispanic,
21% White/Non-Hispanic, and 3% Asian/Pacific
Figure III. TB counted cases by Race and Ethnicity, Palm Beach, Florida, 2004 Risk factor
Birth in a geographic area where TB is endemic was
Seventy-eight (78%) of the 2004 TB cases were
again the most important risk factor for TB among 2004
pulmonary, six (6%) were both pulmonary and extra-
cases, accounting for 67% of the cases. Most foreign-
pulmonary and 15 (15%) were extra-pulmonary only
born TB cases occurred among people born in Haiti
(42.4%) followed by Guatemalan-born (18%) and
Mexican-born (9%) (Figure IV). Thirty-nine percent of foreign-born cases occurred among those who had immigrated to the United States within the previous five years. Among those, 10 came during the previous year and 4 came during the same year they developed TB.
Palm Beach County Health Department, Broadway Health Center TB Control Program
Phone: (561) 882-3110 Fax: (561) 845-4468 E-mail: [email protected]Figure VI. TB cases by site of disease. Palm Beach, Fl 2004
Ninety-one (92%) cases out of the 99 were managed by Palm Beach County Health Centers. The other 8
cases (8%) were managed by private physicians.
Extra pulm .
Figure VIII presents the proportions of cases
managed by each center. Forty-eight (48%) cases were managed by Broadway, 41(41%) by Delray and 10 (10%) by Belle Glade.
Figure VIII. Management of TB active cases by Health Center, Palm Beach, FL 2004
Sixty-five (65%) of the cases were culture positive,
and of those 15 isolates presented a form of drug
resistance (Figure VII). Four isolates were resistant
to isoniazide (INH) alone, six to streptomycin (SM)
alone. Three isolates was resistant to INH and
Belle Glade Broadway
ethambutol (EMB), one was resistant to INH, SM and
EMB, one to INH/SM/EMB and ethionamide. Two isolates were multi-drug resistant (MDR-TB; resistant
to at least INH and Rifampin). Seven (46.5%) of the
Ninety-four (94%) of TB cases received Directly
isolates that showed drug resistant were from foreign-
Observed Therapy (DOT). All TB cases managed
Figure VII. Tuberculosis drug resistance. Palm *************** Beach, Florida, 2004 Do you have questions about TB?
• For more information about TB in English,
Spanish or Creole, you can call the Florida TB
Hotline: 1-800-4TB-INFO
• Case reporting: Phone: (561) 882-3271 / Fax:
Palm Beach County Health Department, Broadway Health Center TB Control Program
Phone: (561) 882-3110 Fax: (561) 845-4468 E-mail: [email protected]
The Patent Act 1970 Section (15) In the matter of the application for Patent No. 9527 /delnp/2007 filed on 10th Dec,2007 M/s Gilad Science Incorporation ……………….Applicant Hearing held on Feb. 24,2011 Present:- 1. Mr. Natrajan Agent for the applicant 2. Dr. Rajendra Lohia Examiner of Patents & Designs DECISION An application for
Hunter Garrity awoke to the click of a gun. His grandparents kept a night-light in the utility room, but either it wasn’t working or someone had killed it—his basement bedroom was pitch-black. His breathing was a shallow whisper in the darkness. For an instant, he wondered if he’d dreamed the A voice: soft, female, vaguely mocking. “I think you dropped this.” He recognized her voice