PALLIATIVE CAREk PAIN(P-A-I-N) (Mnemonic for evaluation) For End of life P hysical (Issues and Orders to cover)
1) Discuss & clarify with patient &/o family &/o DPOA-HC
I interpersonal/social problems N on-acceptance/spiritual distress
b) advance directives (hospitalizations?, antibiotics?)P hysical
c) anticipated sx=s of dying & plan of management
2) Involve & assure staff=s comfort with plan and orders
(Pain)- (make sure of diagnosis (when you can)
3) Document discussions and write orders.
Mech/Inflammatory vs. neuropathic vs. bone)
4) give AGGRESSIVE COMFORT (mnemonic)
a) A NOREX-IA/ A GGITATION E vacuation problems X erostomia O ral candidiasis I atrogenic (radiation/chemo) R eactive depression A cid (gastritis/PUD)
*Acetaminophen) scheduled dose and add PRN narcotics (write p.o. or p.r.)
c) Appetite stimulants: (megestrol, remeron, trazadone)
**dexamethasone: 4-10 mg per day ~Opiates po/pr* sc/iv size liquid A GGITATION (Terminal Delirium)
morphine 5-7.5mg q 4h*. 1-2mg q 1/2hr 15mg 10,20,100mg/5ml
-Haldol 0.5 mg po/sl/sc q 30 min prn delirium
15mg q 12 h* --- 15,30,60,100,200 mg ----
-lorazepam 0.5 mg po/sl/sc q 30 min prn delirium
10 mg q 12 h.* --- 10, 20, 40,80,160 mg ----
G ASTROINTESTINAL
12 mcg/h. q 3 d* ---12, 25,50,75,100mcg/h
-CONSTIPATION(with opiates always start;)
* (these are starting doses-titrate to pain control and tolerance) (NO UPPER LIMITS)
-NAUSEA: Compazine or Haldol or
Tramadol (Ultram) 25mg q 6 hr* 25-100 mg q. 6 hr 50, 100 mg
GENITOURINARY
*************************************************** Antidepressants dose p.o. size
-BLADDER:-discuss incontinence management
Bupropion 37.5 mg q d to 100 mg SR q d. max 300 mg SR 100 & 150 mg SR
Venlafexine (Effexor) 37.5mg (XR) bid; max 225 mg/d 37.5,75,150 mg
R ESPIRATORY
duloxetine 20 mg start, max 60 mg q d. 20, 30, 60 mg
-DYSPNEA AB-R-E-A-T-H A-I-R@ (for correctable causes) Anticonvulsant B ronchospasm
100 mg q.d.B400 mg t.i.d. 100 & 300 mg
I nterpersonal issues
pregabalin 50 mg po t id, max dose 100 mg tid 25,50,75,100 mg
E ffusions Abdominal pain (colicky) (r/o urinary retention or impaction) A irway obstruction
Phenergan 25 mg q 6hr,oxybutinin 5-10 mg t.i.d.,
T hick secretions H emoglobin (low?)
If Bowel obstruction Y M.S. + anticholinergics, if severe Y Octreotide
(For unresponsive dyspnea,ºgive immediate release opiates) Anxiety (pain) (counsel, reassurance, family, friends, pastor) E MOTIONAL SUPPORT
( choose med based on additional benefits ( hydroxyzine for secretions)
S PIRITUAL SUPPORT Medication po im/iv size liquid S ECRETIONS If cough strong º moisten
hydroxyzine 10-50mg q 4h 10-50 mg q 4h 10 & 25 mg 10&25mg/5ml.
If cough weak º dry-up (with anticholinergics)
-for Death Rattle: atropine qtts, glycopyrolate, TD scopalamine
0.5-2 mg t.i.d. 0.5-2 mg q 4h 0.5 & 1 mg
(If unable p.o.)º(sublingual: Dissolve lorazepam in water, give buccally q 1 hr.)
NFLAMATION (FEVER)
-acetaminophen &/or ASA scheduled dose (is best) or PRN,
I nterpersonal/spiritual-->counseling, family,friends,pastors V OLUME(review with family, dehydration has no pain) N on-acceptance--------------> A @ A E MPATHY(secure your own emotional support) For more explanation see Web site: geriatrics.unmc.edu visit GERI Pearls
k Adapted form APrimer of Palliative Care@ Porter Storey MD
Risperidone Treatment of Autistic Disorder: Longer-Term Benefits and Blinded Discontinuation After 6 Months Research Units on Objective: Risperidone is effective for Results: Part I included 63 children. The Pediatric Psychopharmacology per outbursts, and self-injurious behavior Autism Network behaviors may be chronic, there is a needthe Aberrant Behavior Checklist irritab
CNS Muscle Relaxants Clinical Pearls for the Washington Rx Therapeutic Interchange Program (TIP) Steve Riddle, BS Pharm, BCPS Background In 2003, the Washington State Pharmacy and Therapeutics Committee (P&T), the agency directors of the Department of Social and Health Services-Medical Assistance Administration (DSHS-MAA), Labor and Industries (L&I), and the Health Care